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Placental transfer of rh-GH boosts during the 3rd trimester as endogenous placental GH supplants pituitary secretion, but medical importance of exogenous supplementation is unsure.
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Endocrine crosstalk is substantial: somatropin may perhaps antagonize insulin action by using gluconeogenesis improvement, yet it concurrently lessens adiposity by stimulating hormone-sensitive lipase.
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